Herpetic eye disease treatment

Because herpes is a virus, antibiotics such as penicillin are not an effective treatment. The only drugs that will work against herpes infections are antiviral medications. Depending on how serious the herpes zoster ophthalmicus is and what part of the eye is affected, your doctor will recommend antiviral eye pills, drops or both Researchers in the Herpetic Eye Disease Study Group (HEDS), a four-year, national clinical study, found that Zovirax (acyclovir, GlaxoSmithKline) can decrease the incidence of recurrence by 50%. 2 This is especially significant for patients with stromal disease, because it minimizes the risk of vision impairment Herpetic eye disease is the most common infectious cause of corneal blindness in this country. Despite the availability of antiviral agents that are effective in treating herpes simplex epithelial keratitis, inflammation in the corneal connective tissue and iris that can lead to corneal scarring and visual impairment develops in many patients Herpetic Eye Disease Study Group After the resolution of ocular HSV disease, 12 months of treatment with acyclovir reduces the rate of recurrent ocular HSV disease and orofacial HSV disease. Long-term antiviral prophylaxis is most important for patients with a history of HSV stromal keratitis, since it can prevent additional episod

Eye Disease Diagnosis & Treatment | Glaucoma, Cataracts

The Herpetic Eye Disease Study II showed that the live virus and epithelial disease can be suppressed with oral acyclovir. 2 For people who have recurrent issues of live virus, we recommend oral antivirals indefinitely, says Dr. Mah On the basis of both animal and human studies, the antiviral agent acyclovir may both treat and prevent recurrence of HSV disease. However, no consensus yet exists on the use of acyclovir in the management and prevention of herpetic eye disease Ocular herpes: the pathophysiology, management and treatment of herpetic eye diseases Lucy Zhu, Hua Zhu Department of Microbiology, Biochemistry & Molecular Genetics Rutgers, Rutgers - New Jersey Medical School, New Jersey 07103, USA Herpesviruses are a prominent cause of human viral disease, second only to the cold and infl uenza viruses Systemic antivirals—acyclovir, famciclovir or valacyclovir—are the primary treatment because they protect the cornea as well as treat the uveitis

Herpetic Eye Disease: Types, Symptoms, Causes & Treatment

If you promptly take antiviral medication, it can help minimize cornea damage and vision loss. Your doctor will recommend antiviral eye drops or ointment or oral antiviral drugs. A common treatment.. Lubrication: Eyes with previous or current active herpetic eye disease tend to have dryness of the ocular surface, which can slow down the healing process. Actively lubricating the eyes with preservative-free eye drops or gels or ointment (the lubricants are the same as those used for dry eye treatment), help with the recovery process

Ocular HSV: Treatment Options - Review of Optometr

Unfortunately, herpetic eye disease can be painful even after several days of treatment and even when the eye is starting to look better. This can be discouraging, but it does not mean that the. Possible treatments include: Antiviral medicines taken by mouth Antiviral ointment for your eyelids Antibiotic ointment for your eyelids (to prevent further infection by bacteria A landmark trial that was part of the Herpetic Eye Disease Study demonstrated that systemic antiviral therapy with oral acyclovir significantly reduced the frequency of recurrent ocular HSV-1 disease. In patients with a history of stromal disease specifically, oral acyclovir treatment reduced the probability of HSK recurrence by 50%, from 28%. Treatment decisions need to consider the visual impact and costs—direct and indirect—of the types of herpetic eye disease. For epithelial keratitis and other HSV infections of the ocular surface, the prolonged use of oral acyclovir must be weighed against the generally excellent results achieved with short-term topical antiviral therapy Treatments A doctor may prescribe an antiviral eye drop. No cure currently exists for herpetic eye disease. Instead, an eye doctor can prescribe medications that reduce the effects and symptoms of..

Most herpes simplex eye infections get better in 1 to 2 weeks, although they can last longer. Treatment is usually needed to reduce the risk of complications. The main treatments are: antiviral eyedrops or ointment - these stop the virus spreading and are usually used several times a day for up to 2 week The two types of herpes virus that most commonly affect the eyes are herpes simplex virus-1 (HSV-1) (the same virus that causes cold sores on the lips) and varicella-zoster virus (VZV; herpes zoster), which causes chickenpox in childhood and shingles in adulthood.. Less commonly, cytomegalovirus can cause eye disease in immunocompromised people, such as HIV-infected patients with low T cell. In case you have eye herpes, the culture will test positive for type 1 HSV (HSV-1). A correct diagnosis can help you to receive proper treatment and eliminate the disease at the earliest. Treatment Procedure For Ocular Herpes. If your eye specialist has detected the presence of eye herpes, then he will start prescribing anti-viral medications. Disease Entity. Herpes simplex virus (HSV) is a very common, lifelong infection that often is asymptomatic. In the 2015-2016 National Health and Nutrition Examination Survey, the prevalence of HSV type 1 (HSV-1) was 47.8% and HSV type 2 (HSV-2) was 11.9%. Globally, the incidence of HSV keratitis is 1.5 million yearly, including 40,000 new cases. Keratitis (corneal infection and inflammation) caused by herpes simplex virus (HSV) is a major cause of blindness worldwide, due to corneal scarring and opacity [ 1 ]. Keratitis is the most prevalent form of ocular HSV-1 disease. Other forms include eyelid lesions (herpetic blepharitis), conjunctivitis, uveitis, retinitis, and, rarely.

5. Sudesh S, Laibson PR. The impact of the herpetic eye disease studies on the management of herpes simplex virus ocular infections. Curr Opin Ophthalmol. 1999;10(4):230-233. 6. A controlled trial of oral acyclovir for the prevention of stromal keratitis or iritis in patients with herpes simplex virus epithelial keratitis. The Epithelial. Figure 2 Efficacy of an engineered FGF-1, TTHX1114, on the reduction of severity of primary corneal herpetic disease: Mice were treated, or mock treated, with TTHX1114 (1.6 ng/eye, twice a day) from day1 post-infection with HSV-1 McKrae (1 x 10 5 and 5 x 10 5 pfu/eye). Mice were scored for pathological symptoms of blepharitis and Keratitis after infection at day 5, 7, 10, 14, 21 and 28 -days. Ocular herpes: the pathophysiology, management and treatment of herpetic eye diseases. Department of Microbiology, Biochemistry & Molecular Genetics Rutgers, Rutgers -New Jersey Medical School, New Jersey 07103, USA. Abstract: Herpesviruses are a prominent cause of human viral disease, second only to the cold and influenza viruses Based on the experience of 151 patients in Rochester with new or recurrent HSV eye disease per 1.5 million person-years, 1 28 860 people in the United States would be expected to develop herpetic eye disease this year. Treatment and prevention costs for this group would be $66 522 300 per year Herpes zoster is a common infection caused by the human herpesvirus 3, the same virus that causes varicella (i.e., chickenpox). It is a member of the same family (Herpesviridae) as herpes simplex.

The Herpes Zoster virus (HZV) causes shingles and is the same virus that causes chicken pox. The virus remains dormant in the body after a chicken pox infection and can reactivate later. HZV infections involving the eye can appear very similar to an HSV infection. The rash is usually painful and develops on the forehead and around one eye in a. Causes & Symptoms of Eye Herpes. Keratitis, or inflammation or infection of the eyes, has several potential causes, including bacteria, parasites, overexposure to ultraviolet (UV) light, or a virus (specifically HSV-1 or HSV-2). There are roughly 20,000 new reported cases of eye herpes in the United States every year, with 48,000 total reported. Herpes simplex keratitis (HSK) is an important infectious cause of unilateral blindness, as it causes permanent corneal scarring, in developed countries (Figure 1). 1,2 One fifth of people with ocular herpes simplex virus (HSV) develop corneal stromal disease with the attendant risk of blindness. 3 Worldwide, the incidence of HSK in 2012 was estimated at about 1.5 million, with 40,000 new.

Study Medical Photos: Ocular Herpes Simplex

HSV (Herpes Simplex Virus) keratitis is an infection of the cornea—the clear dome that covers the colored part of the eye—that is caused by HSV. The infection usually heals without damaging the eye, but more severe infections can lead to scarring of the cornea or blindness. HSV keratitis is a major cause of blindness worldwide 1 ↑ Wilhelmus KR, Gee L, Hauck WW, et al. Herpetic Eye Disease Study: A Controlled trial of topical corticosteroids for herpes simplex stromal keratitis. Ophthalmology 1994;101:1883 ↑ 16.0 16.1 Herpetic Eye Disease Study Group. Acyclovir and the prevention of recurrent herpes simplex virus eye disease. N Engl J Med 1998:339;30 Herpetic Keratitis Treatment. Most outbreaks of herpetic keratitis will resolve themselves spontaneously within 3 weeks of infection, most treatment options involve minimizing damage to the eye and preventing scarring. Topical and oral therapy are most common, but some other forms of treatment may also be necessary depending on the extent of. Herpes Simplex Keratitis. The most common infectious cause of blindness in the United States, ocular herpes is a devastating and recurrent condition that can eventually scar the cornea such that corneal transplantation is necessary to restore sight. This disease is a major focus of research at the Eye Center, including pharmacological. Herpes simplex virus (HSV) is a leading cause of corneal opacification and infection-related visual loss. An estimated 400,000 Americans have had ocular HSV disease, and there are nearly 50,000.

This can be discouraging but it doesnt mean the treatment is a failure. Herpes simplex keratitis is treated with topical antiviral therapy. Suggest treatment for herpetic eye disease following a corneal ulcer What causes herpes infections in eye with herpes esophagitis? Suffering from conjunctivitis, eyelids swollen Ocular Herpes Twinlight Studios 2021-03-26T07:02:43-04:00. This disease can cause permanent corneal damage if left untreated. It is mainly spread through coming into close contact with persons who have the simplex virus. The virus generally enters the body through the nose or mouth. However, the virus itself must be active to be transmitted to. Herpes infections caused by HSV-1 can sometimes spread to the eye from other areas of the body, which may result in keratoconjunctivitis. This condition, generally called herpes keratitis or herpetic keratitis , affects the conjunctiva and cornea, causing irritation, excess tears, and sensitivity to light Herpes simplex is a virus that causes cold sores and genital herpes.However, it can also cause eye infections. This is because the virus lives inside the nerves in your face and can travel down the nerves to your eye if you are unwell or stressed

Herpetic Eye Disease Study (HEDS) I - Full Text View

  1. However, when the virus invades the eye, a number of pathologies can develop and its associated sequelae have become a considerable source of ocular morbidity. The most common culprits of herpetic eye disease are the herpes simplex virus (HSV), varicella zoster virus (VZV), and cytomegalovirus (CMV)
  2. Treatment Noninfectious keratitis. Treatment of noninfectious keratitis varies depending on the severity. For example, with mild discomfort from a corneal scratch, artificial tear drops may be the only treatment. However, if keratitis is causing significant tearing and pain, a 24-hour eye patch and topical eye medications may be necessary
  3. Herpes zoster ophthalmicus is reactivation of a varicella-zoster virus infection ( shingles) involving the eye. Symptoms and signs, which may be severe, include dermatomal forehead rash and painful inflammation of all the tissues of the anterior and, rarely, posterior structures of the eye. Diagnosis is based on the characteristic appearance of.

Acyclovir for the prevention of recurrent herpes simplex

Key Points about Herpes Zoster Ophthalmicus. The eye is affected in about half of cases of V1 varicella-zoster virus reactivation. Keratitis and/or uveitis can be severe and cause morbidity. Appearance of the typical herpes zoster rash is usually diagnostic. Treatment is with oral antivirals and usually topical corticosteroids and pupillary. The herpes viruses (herpes simplex and herpes zoster) may cause keratitis. Bacteria. The bacterium that causes gonorrhea can cause keratitis. Contaminated water. Bacteria, fungi and parasites in water — particularly in oceans, rivers, lakes and hot tubs — can enter your eyes when you're swimming and result in keratitis The best herpes treatment for you may depend on the type and severity of the infection. Acyclovir (Zovirax) Acyclovir is a prescription antiviral drug taken orally or applied topically that treats. Disease Entity. Herpes simplex virus (HSV) associated uveitis is a common cause of unilateral hypertensive anterior uveitis. Herpetic anterior uveitis causes approximately 5-10% of uveitis cases. Etiology. Herpes simplex iritis is due to the Herpes simplex virus. The most common subtype is HSV-1

The Herpetic Eye Disease Study (HEDS) from the National Eye Institute found that the use of oral acyclovir 400 mg PO BID (or equivalent) was effective in (1) significantly reducing the incidence of recurrent epithelial keratitis and stromal keratitis; (2) possibly effective in reducing the incidence of recurrent endothelial keratitis and. INTRODUCTION — Herpes simplex virus type 1 (HSV-1) is a cause of recurrent vesiculoulcerative lesions of the oral or genital mucosa. It can also cause infection in the eye, skin, central nervous system, and/or visceral organs. This topic will review treatment and prevention of primary and recurrent HSV-1 infections in immunocompetent adolescents and adults Eye diseases like retinitis pigmentosa, retinopathy of prematurity, and vernal keratoconjunctivitis, along with Down syndrome, osteogenesis imperfecta, Addison's disease, Leber's congenital. When it affects a person's eyes, the condition is known as eye herpes, ocular herpes, or herpetic eye disease. Eye herpes may be a cause for concern because it can have uncomfortable symptoms However, conjunctival or corneal scrapings for cytologic examination can be useful to eliminate other disease conditions from consideration (e.g., eosinophilic keratitis). If a cat has ocular disease consistent with FHV and has not received antiviral treatment, the best approach is to initiate such treatment. Antiviral agent

How to Manage Ocular Herpes - Review of Ophthalmolog

  1. The clinical signs of feline herpes varies; some patients have very mild disease with temporary watering of the eyes, while other patients have chronic or severe ocular disease. Treatment is aimed at stopping viral replication and protecting against secondary bacterial infection when the disease is active
  2. Zirgan Herpes Keratitis Treatment Zirgan is the Best Treatment for Herpes Keratitis (Ganciclovir ophthalmic gel) 0.15% by Bausch & Lomb. The herpes simplex virus (HSV) can attack the eye and result in herpetic keratitis, which is a significant cause of corneal damage that can even lead to blindness
  3. Treatment of herpes simplex keratitis involves the use of eye drops, systemic medications and/or ointments. The drop most often used for this condition is Viroptic® (generic: trifluridine), a potent antiviral agent. Vira A® (generic: vidarabine), an ophthalmic ointment may also be used in combination with Viroptic or on its own for the primary form of the disease

Herpetic Eye Disease Study (HEDS) II - Full Text View

  1. In Meyler's Side Effects of Drugs (Sixteenth Edition), 2016. General information. Intravenous vidarabine is effective in the treatment of kerato-uveitis in animals and man, and has been used intravenously to treat herpetic eye infections in man [1].It has also been used as an ointment for treating superficial keratitis that does not respond to idoxuridine, but it penetrates the eye poorly [2]
  2. Herpetic Eye Disease Study Group. A controlled trial of oral acyclovir for the prevention of stromal keratitis or iritis in patients with herpes simplex virus epithelial keratitis. The Epithelial Keratitis Trial. Arch Ophthalmol. 1997 Jun. 115(6):703-12. . Herpetic Eye Disease Study Group
  3. The Herpetic Eye Disease Study Group found that using prophylactic oral acyclovir helped to prevent relapses in patients with recurrent herpetic eye disease, but the study group excluded patients.
  4. Sometimes the herpetic uveitis causes glaucoma. That is, the inflammation blocks the drainage of fluid in the eye .This condition is termed herpetic uveitis. Treatment is antiviral tablets Aciclovir 400mg 5 times a day initially, probably steroid drops, but also drops to lower the eye pressure
  5. Topical ocular antiviral therapy: These anti-herpes drugs, known as idoxuridine, trifluridine, and cidofovir, can be used as eye drops in treating cat herpes. Eye drops are usually given daily and sometimes combined with other treatment options
  6. This includes dry eye disease (keratoconjunctivitis sicca), exposure keratitis, limbal stem cell deficiency, damage to the cornea following surgery, and Sjogren syndrome. Diagnosis A diagnosis of neurotrophic keratitis is based upon identification of characteristic symptoms, a detailed patient and family history, a thorough clinical evaluation.
  7. d: a full cure from the threat of a chronic, lifelong disease
Feline Herpes - Northwest Animal Eye Specialists

In some patients, this is a good time to start antiviral treatments to try to prevent the eye problems. SUMMARY: Herpes infections cause some of the most common eye problems of cats. There is not a week that goes by where we don't see a cat (usually many) with herpetic eye disease. We deal with this all of the time and are here to help you Herpes simplex encephalitis is a rare neurological condition that is characterized by inflammation of the brain (encephalitis). People affected by this condition may experience a headache and fever for up to 5 days, followed by personality and behavioral changes; seizures; hallucinations; and altered levels of consciousness.Without early diagnosis and treatment, severe brain damage or even. What is the Zoster Eye Disease Study (ZEDS)? A multi-center randomized clinical trial (RCT) to look at whether long-term treatment will be effective in decreasing eye disease and/or chronic pain in patients with a form of shingles, called Herpes Zoster Ophthalmicus, which affects the eye After antiviral treatment, trabeculectomy was carried out in the right eye, when latanoprost treatment was continued in the left eye. After a small period of time, in the right eye—without latanoprost treatment—there was no herpetic infection, while in the left eye—with latanoprost treatment—herpetic infection presented again Treatment should generally be initiated by an ophthalmologist and should include a topical corticosteroid and a cycloplegic-mydriatic drug. Acyclovir (400 mg orally 5 times/day for HSV and 800 mg orally 5 times/day for herpes zoster virus [HZV]) or valacyclovir (1

The herpes zoster infection was mild in the majority of cases, although one patient had a case of herpes zoster ophthalmicus, which is when the virus impacts the eye The landmark study of long-term use of oral acyclovir for the prevention of recurrent Herpes Simplex Virus (HSV) ocular disease, the Herpetic Eye Disease Study (HEDS) Acyclovir Prevention Trial (APT), demonstrated a 45% reduction in recurrent ocular disease over one year, and was most beneficial for patients with a past history of HSV stromal. Herpetic simplex keratitis is a form of keratitis caused by recurrent herpes simplex virus (HSV) infection in the cornea.. It begins with infection of epithelial cells on the surface of the eye and retrograde infection of nerves serving the cornea. Primary infection typically presents as swelling of the conjunctiva and eyelids (blepharoconjunctivitis), accompanied by small white itchy lesions. Keratoplasty or keratorefractive surgery of the involved eye with zoster. On systemic antivirals with activity against herpes within the past 30 days, including acyclovir, valacyclovir, or famciclovir, for any reason except for treatment of acute HZO, including investigational drug trial

Understanding and Treating Viral Anterior Uveitis

The herpes sore on lip primary disease, the role in the virus type 1 infection or sores, zovirax cream was the need to note that reducing the eye, herpes infection may vary among patients were body weight humectant/solvents propylene glycol is a co-infection. Or any blisters or more than the sores are specifically merkel cell transplantation. Herpes simplex virus (HSV) is the most common infective cause of blindness in developed countries, with a reported incidence of 5.9 to 20.7 episodes per 100,000 persons each year. 1 In 1992, the National Eye Institute (NEI) sponsored the Herpetic Eye Disease Study (HEDS) to improve the care and treatment of periocular infection

Eye Herpes: Symptoms, Treatment, and Mor

Epithelial Keratitis, Stromal Disease, and Endotheliitis. While ocular herpes can cause a variety of eye complications, the most serious is keratitis. There are essentially two types of keratitis: epithelial disease and stromal disease. Epithelial keratitis can cause redness, photophobia, tearing, blurred vision, and more in an infected eye What Are The Different Forms Of Eye Herpes? Eye herpes can come in several forms and can even result in blindness. Four forms of eye herpes include: #1 Herpes Keratitis is the most common form of eye herpes. Herpes keratitis is a type of eye herpes that can cause a viral corneal infection

Herpetic Eye Disease - What It Is, What Causes It, and How

Herpes simplex eye disease occurs when the virus or a reaction against it occurs in one of the ocular structures. Inflammation and infection at one of the anatomic levels of the cornea is most common. Usually, only one eye is involved (and it can recur), often without typical skin lesions. Spreading the infection to another person is unlikely. Treatment of herpetic keratitis . There is no complete cure for herpes at this time, and the virus may be reactivated (see above). Your eye care professional will determine a course of action depending on the severity of your symptoms. This may include: Topical medication; Oral antiviral medicatio Briefly speaking, it is an eye infection but the inflammation caused by the herpes virus can spread from the eye's surface layers to deeper parts of the cornea if no proper treatment is applied. Active herpes virus in the eye can be contagious through close contact, bringing inflammation and scarring of the cornea Herpes and the Eye. Herpes! The first thought in most people's mind is venereal disease, sexual transmitted disease (STD). But, in fact most instances of herpes, at least those affecting the eye, are not sexually transmitted, and are not even the type of herpes that is usually associated with sexually transmitted disease Corneal Disease. The term corneal disease covers the variety of conditions that affect the cornea, the clear outer layer of the eye. The cornea can often repair itself after injury or disease, but more serious conditions -- infections, degenerative diseases, deterioration -- need treatment. Appointments 216.444.2020. Appointments & Locations

Herpes simplex virus keratitis: an update of the

Persistence of herpes simplex virus type 1 DNA in chronic conjunctival and eyelid lesions of mice. Journal of virology, 72(11), 9166-9172. Whitley, R. J. (1997). Herpes simplex virus. Infections of the central nervous system, 2, 73-89. Baum, J. (1995). Infections of the eye. Clinical infectious diseases, 479-486 Minor kitten eye infections due to herpes may clear up on their own, without treatment. However, if you're not sure what may be wrong with your cat, it's always a good idea to take them to the vet, especially when they have eye problems. When eye problems go untreated, they can potentially lead to vision problems or even blindness Herpes Simplex Keratitis Eye Infection. Herpes Simplex Keratitis or simply herpes keratitis (sometimes referred to as dendritic keratitis) is an infection of the cornea of the eye by the herpes simplex virus type 1 (HSV1), which can cause serious vision loss including blindness.It is estimated that 80% of the U.S. population harbors this virus! At least two thirds of those infected do not have. Eye herpes, or ocular herpes, is a viral infection caused by the herpes simplex virus (HSV). Herpes infections that affect the eye are usually caused by HSV type 1 infections, which are also a common cause of cold sores and blisters on the face, rather than type 2 infections, which affect the genitals. In rare cases, an infant can develop an HSV 2 infection during birth when the mother is.

Herpes Simplex Keratitis - Asia Pacific - American AcademyEye Problems in Dogs and Cats—Treatment of Corneal Ulcers

Herpes zoster ophthalmicus (HZO) is a serious, vision-threatening infection that affects the eye and the skin surrounding the eye. HZO is caused by reactivation of the varicella-zoster virus, the same virus that causes chickenpox in children. After infection, the virus remains dormant in the nerves and can reactivate, resulting in shingles in people with weakened immune systems Definition. Neurotrophic keratitis (NK) is a rare degenerative corneal disease caused by impairment of trigeminal innervation leading to corneal epithelial breakdown, impairment of healing, and development of corneal ulceration, melting, and perforation. 1 The hallmark of NK is a decrease or absence of corneal sensation. 1, 2 NK was initially described as neuroparalytic keratitis and. Herpes Zoster Ophthalmicus: Herpes zoster ophthalmicus (HZO) is characterized by a vesiculobullous rash over the ophthalmic branch of the trigeminal nerve and may be associated with keratitis, conjunctivitis, blepharitis, and uveitis.() Although HZO most commonly affects individuals in the sixth and seventh decades of life, it may be an initial manifestation of HIV infection in young persons. Fibroblast Growth Factor-1 Cures Ocular Herpes 1 1 2 Healing of Primary and Recurrent Mouse Ocular Herpetic Disease Following Topical Ocular 3 Treatment with an Engineered Fibroblast Growth Factor-1 (FGF-1) is Associated with Increased 4 Frequency and Function of Corneal Anti-Inflammatory M2 Macrophages 5 6 Nisha R Dhanushkodi1, Ruchi Srivastava1, Pierre-Gregoire A. Coulon1, Swayam Prakash1 Treatment for Herpes Eye Disease. Herpes eye disease is a condition caused by the herpes simplex virus. It causes redness, pain, tearing, and other symptoms in the eyes. It's a common condition for people who have been exposed to the herpes virus. In severe cases, it can cause loss of eyesight

Acute Retinal Necrosis After Herpes Zoster Vaccination

When one of the herpes viruses, herpes simplex 1 or herpes zoster, manifests in the eyes, it is called ocular herpes or herpetic eye disease. Ocular herpes may cause scarring, chronic inflammation, lesions, and ulcers that damage different layers of the cornea. It is the most common infectious cause of corneal blindness in the U.S Treatment and cure for herpetic eye disease Download Here Free HealthCareMagic App to Ask a Doctor All the information, content and live chat provided on the site is intended to be for informational purposes only, and not a substitute for professional or medical advice Herpetic Eye Disease Study Group. A controlled trial of oral acyclovir for iridocyclitis caused by herpes simplex virus. Arch Ophthalmol. 1996 Sep. 114(9):1065-72. . Herpetic Eye Disease Study Group. Acyclovir for the prevention of recurrent herpes simplex virus eye disease. N Engl J Med. 1998 Jul 30. 339(5):300-6.